TRAP1 Antikörper (Internal Region)
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- Target Alle TRAP1 Antikörper anzeigen
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- TRAP1 Antibody detects endogenous levels of total TRAP1.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TRAP1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TRAP1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
- Andere Bezeichnung
- TRAP1 (TRAP1 Produkte)
- Synonyme
- HSP 75 antikoerper, HSP75 antikoerper, HSP90L antikoerper, TRAP-1 antikoerper, 2410002K23Rik antikoerper, fc85a11 antikoerper, wu:fc85a11 antikoerper, TNF receptor associated protein 1 antikoerper, TNF receptor-associated protein 1 antikoerper, TRAP1 antikoerper, Trap1 antikoerper, trap1 antikoerper
- Hintergrund
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Description: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
Gene: TRAP1
- Molekulargewicht
- 80kDa
- Gen-ID
- 10131
- UniProt
- Q12931
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