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TRAP1 Antikörper (Internal Region)

TRAP1 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265714
  • Target Alle TRAP1 Antikörper anzeigen
    TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
    Bindungsspezifität
    • 15
    • 10
    • 10
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 111
    • 43
    • 29
    • 5
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 93
    • 33
    Kaninchen
    Klonalität
    • 86
    • 39
    Polyklonal
    Konjugat
    • 40
    • 10
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRAP1 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 34
    • 29
    • 26
    • 21
    • 20
    • 13
    • 13
    • 12
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    TRAP1 Antibody detects endogenous levels of total TRAP1.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TRAP1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product TRAP1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
    Andere Bezeichnung
    TRAP1 (TRAP1 Produkte)
    Synonyme
    HSP 75 antikoerper, HSP75 antikoerper, HSP90L antikoerper, TRAP-1 antikoerper, 2410002K23Rik antikoerper, fc85a11 antikoerper, wu:fc85a11 antikoerper, TNF receptor associated protein 1 antikoerper, TNF receptor-associated protein 1 antikoerper, TRAP1 antikoerper, Trap1 antikoerper, trap1 antikoerper
    Hintergrund

    Description: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

    Gene: TRAP1

    Molekulargewicht
    80kDa
    Gen-ID
    10131
    UniProt
    Q12931
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