TRF1 Antikörper (Internal Region)
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- Target Alle TRF1 (TERF1) Antikörper anzeigen
- TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- TRF1 Antibody detects endogenous levels of total TRF1.
- Homologie
- Horse,Sheep
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TRF1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TERF1 Primärantikörper
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- Applikationshinweise
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
- Andere Bezeichnung
- TERF1 (TERF1 Produkte)
- Synonyme
- PIN2 antikoerper, TRBF1 antikoerper, TRF antikoerper, TRF1 antikoerper, hTRF1-AS antikoerper, t-TRF1 antikoerper, wu:fb74c04 antikoerper, TERF1 antikoerper, DKFZp459A0713 antikoerper, Pin2 antikoerper, Trbf1 antikoerper, Trf1 antikoerper, terf1 antikoerper, trf1 antikoerper, telomeric repeat binding factor 1 antikoerper, telomeric repeat binding factor (NIMA-interacting) 1 antikoerper, telomeric repeat binding factor (NIMA-interacting) 1 L homeolog antikoerper, TERF1 antikoerper, Terf1 antikoerper, terf1 antikoerper, Trf1 antikoerper, terf1.L antikoerper
- Hintergrund
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Description: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
Gene: TERF1
- Molekulargewicht
- 50kDa
- Gen-ID
- 7013
- UniProt
- P54274
- Pathways
- Zellzyklus, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
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