TSG101 Antikörper

Produktnummer ABIN6265767

Produktdetails anti-TSG101 Antikörper

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSG101 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: TSG101 Antibody detects endogenous levels of total TSG101

Kreuzreaktivität: Human, Affe

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TSG101

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu TSG101

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Andere Bezeichnung: TSG101 (TSG101 Produkte)

Synonyme: CG9712 antikoerper, DmTSG101 antikoerper, Dmel\\CG9712 antikoerper, ESCRT-I antikoerper, Tsg101 antikoerper, burs antikoerper, dTSg101 antikoerper, dTsg101 antikoerper, dVps23 antikoerper, ept antikoerper, tsg101 antikoerper, vps23 antikoerper, TSG101 antikoerper, MGC76193 antikoerper, TSG10 antikoerper, VPS23 antikoerper, AI255943 antikoerper, CC2 antikoerper, Rw antikoerper, zgc:86926 antikoerper, tumor susceptibility 101 antikoerper, Tumor susceptibility gene 101 antikoerper, Tumor Susceptibility Gene homolog antikoerper, tumor susceptibility gene 101 antikoerper, tumor susceptibility 101a antikoerper, tumor susceptibility 101 L homeolog antikoerper, TSG101 antikoerper, tsg-101 antikoerper, tsg101 antikoerper, Tsg101 antikoerper, tsg101a antikoerper, tsg101.L antikoerper

Hintergrund:

Description: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed:22315426).

Gene: TSG101

Molekulargewicht: 45 kDa

Gen-ID: 7251

UniProt: Q99816