TSHZ3 Antikörper (Internal Region)
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- Target Alle TSHZ3 Antikörper anzeigen
- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TSHZ3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- TSH3 Antibody detects endogenous levels of total TSH3.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TSH3, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TSHZ3 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
- Andere Bezeichnung
- TSHZ3 (TSHZ3 Produkte)
- Synonyme
- ZNF537 antikoerper, A630038G13Rik antikoerper, Tsh3 antikoerper, Zfp537 antikoerper, mKIAA1474 antikoerper, teashirt3 antikoerper, TSH3 antikoerper, teashirt zinc finger homeobox 3 antikoerper, teashirt zinc finger family member 3 antikoerper, TSHZ3 antikoerper, Tshz3 antikoerper
- Hintergrund
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Description: Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s) (PubMed:19343227). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter (By similarity). Involved in the modulation of glutamatergic synaptic transmission and long-term synaptic potentiation (By similarity).
Gene: TSHZ3
- Molekulargewicht
- 119 kDa
- Gen-ID
- 57616
- UniProt
- Q63HK5
- Pathways
- Regulation of Muscle Cell Differentiation
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