NPRL2 Antikörper (C-Term)

Produktnummer ABIN6265808

Produktdetails anti-NPRL2 Antikörper

Target: NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPRL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: TUSC4 Antibody detects endogenous levels of total TUSC4.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TUSC4, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NPRL2

Target: NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))

Andere Bezeichnung: NPRL2 (NPRL2 Produkte)

Synonyme: 2810446G01Rik antikoerper, G21 antikoerper, NPR2L antikoerper, Tusc4 antikoerper, npr2 antikoerper, npr2l antikoerper, tusc4 antikoerper, NPR2 antikoerper, TUSC4 antikoerper, im:6900399 antikoerper, zgc:153630 antikoerper, nitrogen permease regulator-like 2 antikoerper, NPR2 like, GATOR1 complex subunit S homeolog antikoerper, NPR2 like, GATOR1 complex subunit antikoerper, NPR2-like, GATOR1 complex subunit antikoerper, Nprl2 antikoerper, nprl2.S antikoerper, NPRL2 antikoerper, nprl2 antikoerper

Hintergrund:

Description: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

Gene: NPRL2

Molekulargewicht: 44 kDa

Gen-ID: 10641

UniProt: Q8WTW4