UBA52 Antikörper
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- Target Alle UBA52 Antikörper anzeigen
- UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UBA52 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- UBA52 Antibody detects endogenous levels of total UBA52
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human UBA52
- Isotyp
- IgG
- Top Product
- Discover our top product UBA52 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
- Andere Bezeichnung
- UBA52 (UBA52 Produkte)
- Synonyme
- CEP52 antikoerper, HUBCEP52 antikoerper, L40 antikoerper, RPL40 antikoerper, D8Ertd21e antikoerper, Gm1863 antikoerper, Rps27a antikoerper, Ubb antikoerper, Ubc antikoerper, UBCEP2 antikoerper, UB-RPL40 antikoerper, MGC80109 antikoerper, cep52 antikoerper, hubcep52 antikoerper, rpl40 antikoerper, RPS27A antikoerper, UBB antikoerper, UBC antikoerper, wu:fa91f08 antikoerper, zgc:123344 antikoerper, UBA52 antikoerper, ubiquitin A-52 residue ribosomal protein fusion product 1 antikoerper, ubiquitin A-52 residue ribosomal protein fusion product 1 L homeolog antikoerper, UBA52 antikoerper, Uba52 antikoerper, uba52.L antikoerper, uba52 antikoerper
- Hintergrund
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Description: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Gene: UBA52
- Molekulargewicht
- 15 kDa
- Gen-ID
- 7311
- UniProt
- P62987
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation
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