WASF1 Antikörper (Internal Region)
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- Target Alle WASF1 Antikörper anzeigen
- WASF1 (WAS Protein Family, Member 1 (WASF1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WASF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- WAVE1 Antibody detects endogenous levels of total WAVE1.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human WAVE1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product WASF1 Primärantikörper
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- Applikationshinweise
- WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- WASF1 (WAS Protein Family, Member 1 (WASF1))
- Andere Bezeichnung
- WASF1 (WASF1 Produkte)
- Hintergrund
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Description: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
Gene: WASF1
- Molekulargewicht
- 70kDa
- Gen-ID
- 8936
- UniProt
- Q92558
- Pathways
- RTK Signalweg, Regulation of Actin Filament Polymerization
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