WNT7A Antikörper (Internal Region)
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- Target Alle WNT7A Antikörper anzeigen
- WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WNT7A Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- Wnt7a Antibody detects endogenous levels of total Wnt7a.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Wnt7a, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product WNT7A Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))
- Andere Bezeichnung
- WNT7A (WNT7A Produkte)
- Synonyme
- wnt7a antikoerper, AI849442 antikoerper, Wnt-7a antikoerper, px antikoerper, tw antikoerper, Xwnt-7a antikoerper, wnt-7a antikoerper, wnt7a-A antikoerper, Wnt family member 7A antikoerper, wingless-type MMTV integration site family, member 7Aa antikoerper, wingless-type MMTV integration site family, member 7A antikoerper, wingless-type MMTV integration site family member 7A S homeolog antikoerper, WNT7A antikoerper, wnt7aa antikoerper, Wnt7a antikoerper, wnt7a.S antikoerper
- Hintergrund
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Description: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development (PubMed:16826533). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal neural stem cell proliferation in the hippocampus dentate gyrus. Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation. Promotes formation of synapses via its interaction with FZD5 (By similarity).
Gene: WNT7A
- Molekulargewicht
- 39kDa
- Gen-ID
- 7476
- UniProt
- O00755
- Pathways
- WNT Signalweg, Stem Cell Maintenance, Asymmetric Protein Localization
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