KISS1R Antikörper (C-Term)

Produktnummer ABIN6266239

Produktdetails anti-KISS1R Antikörper

Target: KISS1R (KISS1 Receptor (KISS1R))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KISS1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: KISS1R Antibody detects endogenous levels of total KISS1R.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KISS1R, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Andere Bezeichnung: KISS1R (KISS1R Produkte)

Synonyme: AXOR12 antikoerper, CPPB1 antikoerper, GPR54 antikoerper, HH8 antikoerper, HOT7T175 antikoerper, KISS-1R antikoerper, Gpr54 antikoerper, KiSS-1 antikoerper, gpr54 antikoerper, gpr54-1 antikoerper, gpr54a antikoerper, kiss1r antikoerper, kiss1rl antikoerper, kissr2 antikoerper, si:dkey-31m5.9 antikoerper, axor12 antikoerper, kissr1a antikoerper, KISS1 receptor antikoerper, KISS1 receptor a antikoerper, KISS1R antikoerper, Kiss1r antikoerper, kiss1ra antikoerper, kiss1r antikoerper

Hintergrund:

Description: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Gene: KISS1R

Molekulargewicht: 43kDa

Gen-ID: 84634

UniProt: Q969F8