PARD6A Antikörper (N-Term)

Produktnummer ABIN6266264

Produktdetails anti-PARD6A Antikörper

Target: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARD6A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PARD6A Antibody detects endogenous levels of total PARD6A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PARD6A, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PARD6A

Target: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Andere Bezeichnung: PARD6A (PARD6A Produkte)

Synonyme: PARD6A antikoerper, 0710008C04Rik antikoerper, 2610010A15Rik antikoerper, PAR6alpha antikoerper, Par-6 antikoerper, Par6 antikoerper, Par6c antikoerper, TAX40 antikoerper, Tip-40 antikoerper, Par-6a antikoerper, Par6a antikoerper, PAR-6A antikoerper, PAR6 antikoerper, PAR6C antikoerper, TIP-40 antikoerper, par-6 partitioning defective 6 homolog alpha (C. elegans) antikoerper, par-6 family cell polarity regulator alpha antikoerper, Partitioning defective protein 6 antikoerper, PARD6A antikoerper, Pard6a antikoerper, par-6 antikoerper

Hintergrund:

Description: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10873802). Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization (PubMed:20719959).

Gene: PARD6A

Molekulargewicht: 37kDa

Gen-ID: 50855

UniProt: Q9NPB6

Pathways: Cell-Cell Junction Organization