Pleiotrophin Antikörper (C-Term)

Produktnummer ABIN6266311

Produktdetails anti-Pleiotrophin Antikörper

Target: Pleiotrophin (PTN)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Pleiotrophin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: PTN Antibody detects endogenous levels of total PTN.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PTN, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Pleiotrophin

Target: Pleiotrophin (PTN)

Andere Bezeichnung: PTN (PTN Produkte)

Synonyme: zHBNF antikoerper, zgc:111787 antikoerper, harp antikoerper, hbnf antikoerper, X-PTF antikoerper, hbgf8 antikoerper, negf1 antikoerper, ptn antikoerper, PTN antikoerper, HARP antikoerper, HBGF8 antikoerper, HBNF antikoerper, NEGF1 antikoerper, PTN-A antikoerper, HB-GAM antikoerper, HBBM antikoerper, HBGF-8 antikoerper, OSF-1 antikoerper, HBBN antikoerper, OSF antikoerper, Osf-1 antikoerper, Osf1 antikoerper, Hbnf antikoerper, pleiotrophin antikoerper, pleiotrophin L homeolog antikoerper, ptn antikoerper, PTN antikoerper, ptn.L antikoerper, Ptn antikoerper

Hintergrund:

Description: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).

Gene: PTN

Molekulargewicht: 19kDa

Gen-ID: 5764

UniProt: P21246

Pathways: RTK Signalweg