ADGRE2 Antikörper

Produktnummer ABIN6290303

Produktdetails anti-ADGRE2 Antikörper

Target: ADGRE2 (Adhesion G protein-coupled Receptor E2 (ADGRE2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADGRE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human EMR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Expression is restricted to myeloid cells, Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas, Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested, High expression in mast cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu ADGRE2

Target: ADGRE2 (Adhesion G protein-coupled Receptor E2 (ADGRE2))

Andere Bezeichnung: ADGRE2 (ADGRE2 Produkte)

Synonyme: CD312 antikoerper, adhesion G protein-coupled receptor E2 antikoerper, ADGRE2 antikoerper

Hintergrund: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht: 90.472 kDa

Gen-ID: 30817

UniProt: Q9UHX3