IFI16 Antikörper
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- Target Alle IFI16 Antikörper anzeigen
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFI16 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human IFI16
- Isotyp
- IgG
- Top Product
- Discover our top product IFI16 Primärantikörper
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- Applikationshinweise
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - Kommentare
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Expressed in peripheral blood leukocytes, fibroblasts and lymphoid cells, Present in myeloid precursors (CD34+) and throughout monocyte development, but its expression is down-regulated in erythroid and polymorphonuclear precursor cells, Present in prostate, ovary and breast (at protein level)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
- Andere Bezeichnung
- IFI16 (IFI16 Produkte)
- Synonyme
- IFNGIP1 antikoerper, PYHIN2 antikoerper, IFI16 antikoerper, Ifitm3l antikoerper, Ifitml antikoerper, interferon gamma inducible protein 16 antikoerper, interferon induced transmembrane protein 2 antikoerper, myeloid cell nuclear differentiation antigen-like protein antikoerper, interferon-activable protein 203 antikoerper, IFI16 antikoerper, Ifitm2 antikoerper, LOC100156073 antikoerper, LOC488622 antikoerper, Ifi16 antikoerper
- Hintergrund
- This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 88.256 kDa
- Gen-ID
- 3428
- UniProt
- Q16666
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagie, Inflammasome
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