S100A12 Antikörper
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- Target Alle S100A12 Antikörper anzeigen
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser S100A12 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human S100A12
- Isotyp
- IgG
- Top Product
- Discover our top product S100A12 Primärantikörper
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- Applikationshinweise
- IHC 1:50 - 1:100
- Kommentare
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Predominantly expressed by neutrophils, monocytes and activated macrophages, Expressed by eosinophils and macrophages in asthmatic airways in regions where mast cells accumulate, Found in high concentrations in the serum of patients suffering from various inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and Kawasaki disease
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
- Andere Bezeichnung
- S100A12 (S100A12 Produkte)
- Synonyme
- CAAF1 antikoerper, CAGC antikoerper, CGRP antikoerper, ENRAGE antikoerper, MRP-6 antikoerper, MRP6 antikoerper, p6 antikoerper, CO-AG antikoerper, EN-RAGE antikoerper, S100 calcium binding protein A12 antikoerper, protein S100-A12 antikoerper, S100A12 antikoerper, LOC101103771 antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
- Molekulargewicht
- 10.575 kDa
- Gen-ID
- 6283
- UniProt
- P80511
- Pathways
- Toll-Like Receptors Cascades, S100 Proteine
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