BSCL2 Antikörper

Produktnummer ABIN6293870

Produktdetails anti-BSCL2 Antikörper

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BSCL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human BSCL2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Expressed in motor neurons in the spinal cord and cortical neurons in the frontal lobe (at protein level), Highly expressed in brain, testis and adipose tissue

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Andere Bezeichnung: BSCL2 (BSCL2 Produkte)

Synonyme: GNG3LG antikoerper, HMN5 antikoerper, SPG17 antikoerper, 2900097C17Rik antikoerper, AI046355 antikoerper, Gng3lg antikoerper, BSCL2, seipin lipid droplet biogenesis associated antikoerper, Berardinelli-Seip congenital lipodystrophy 2 (seipin) antikoerper, BSCL2 antikoerper, Bscl2 antikoerper

Hintergrund: This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).

Molekulargewicht: 44.392 kDa

Gen-ID: 26580

UniProt: Q96G97