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IGKV1D-16 Antikörper

IGKV1D-16 Reaktivität: Human IHC, FACS, WB, IF Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6296346
  • Target Alle IGKV1D-16 Produkte
    IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))
    Reaktivität
    Human
    Wirt
    • 1
    Maus
    Klonalität
    • 1
    Monoklonal
    Konjugat
    • 1
    Dieser IGKV1D-16 Antikörper ist unkonjugiert
    Applikation
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)
    Verwendungszweck
    Mouse anti-Human Kappa Light Chain Antibody [Sodium Azide Free]
    Spezifität
    Cell surface, cytoplasmic and secreted
    Aufreinigung
    Human B-Lymphoma Cells were used as the immunogen for this Kappa light chain antibody.
    Immunogen
    Human B-Lymphoma Cells were used as the immunogen for this Kappa light chain antibody.
  • Applikationshinweise
    FACS: 0.5-2.0 μg/million cells
    IF: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))
    Andere Bezeichnung
    Immunoglobulin kappa variable 1D-16 (IGKV1D-16 Produkte)
    Synonyme
    IGKV1D16 antikoerper, L15 antikoerper, L15a antikoerper, immunoglobulin kappa variable 1D-16 antikoerper, IGKV1D-16 antikoerper
    Hintergrund

    Target Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

    Gene Symbol: IGKV1D-16///IGKC

    Gen-ID
    3514
    UniProt
    P01601, P01834
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