IGLV1-51 Antikörper

Produktnummer ABIN6296841

Produktdetails anti-IGLV1-51 Antikörper

Target: IGLV1-51 (Immunoglobulin lambda Variable 1-51 (IGLV1-51))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGLV1-51 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Verwendungszweck: Mouse anti-Human Lambda Light Chain Antibody Cocktail [IHC only]

Spezifität: Cell surface, cytoplasmic and secreted

Aufreinigung: Purified human Ig (LcN-2 and ICO-106) was used as the immunogen for this Lambda light chain antibody cocktail.

Immunogen: Purified human Ig (LcN-2 and ICO-106) was used as the immunogen for this Lambda light chain antibody cocktail.

Anwendungsinformationen

Applikationshinweise: Prediluted format : incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu IGLV1-51

Target: IGLV1-51 (Immunoglobulin lambda Variable 1-51 (IGLV1-51))

Andere Bezeichnung: Immunoglobulin lambda variable 1-51 (IGLV1-51 Produkte)

Synonyme: IGLV151 antikoerper, V1-19 antikoerper, immunoglobulin lambda variable 1-51 antikoerper, IGLV1-51 antikoerper

Hintergrund:

Target Description: This antibody cocktail is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Lambda light chain antibody is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Gene Symbol: IGLV1-51///IGLC1

Gen-ID: 3535

UniProt: P01701, P0CG04