TSH receptor Antikörper
-
- Target Alle TSH receptor (TSHR) Antikörper anzeigen
- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser TSH receptor Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Verwendungszweck
- Mouse anti-Human Thyroid Stimulating Hormone Receptor / TSHR Antibody (alpha chain) [Sodium Azide Free]
- Spezifität
- Cytoplasmic, cell surface
- Aufreinigung
- Recombinant human TSH Receptor alpha chain protein was used as the immunogen for this TSHR antibody.
- Immunogen
- Recombinant human TSH Receptor alpha chain protein was used as the immunogen for this TSHR antibody.
- Top Product
- Discover our top product TSHR Primärantikörper
-
-
- Applikationshinweise
-
FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- In 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
- Target
- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
- Andere Bezeichnung
- Thyrotropin receptor (TSHR Produkte)
- Synonyme
- CHNG1 antikoerper, LGR3 antikoerper, hTSHR-I antikoerper, AI481368 antikoerper, hypothroid antikoerper, hyt antikoerper, pet antikoerper, TSHRA antikoerper, TSH-R antikoerper, thyroid stimulating hormone receptor antikoerper, tshr antikoerper, TSHR antikoerper, Tshr antikoerper
- Hintergrund
-
Target Description: Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Graves disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
Gene Symbol: TSHR///LGR3
- Gen-ID
- 7253
- UniProt
- P16473
- Pathways
- Thyroid Hormone Synthesis
-