Insulin Antikörper
-
- Target Alle Insulin (INS) Antikörper anzeigen
- Insulin (INS)
-
Reaktivität
- Human, Schwein, Maus, Rind (Kuh), Ratte
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Insulin Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (IHC)
- Verwendungszweck
- Mouse anti-Human/Cow Pig/Mouse/Rat Insulin Antibody [IHC only]
- Spezifität
- Cytoplasmic
- Aufreinigung
- Recombinant INS protein was used as the immunogen for the Insulin antibody.
- Immunogen
- Recombinant INS protein was used as the immunogen for the Insulin antibody.
- Top Product
- Discover our top product INS Primärantikörper
-
-
- Applikationshinweise
- Prediluted format : incubate for 30 min at RT (2)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
- Target
- Insulin (INS)
- Andere Bezeichnung
- Insulin (INS Produkte)
- Synonyme
- IDDM2 antikoerper, ILPR antikoerper, IRDN antikoerper, MODY10 antikoerper, ins1 antikoerper, xins antikoerper, ins1-a antikoerper, Insulin antikoerper, AA986540 antikoerper, Ins-2 antikoerper, InsII antikoerper, Mody antikoerper, Mody4 antikoerper, proinsulin antikoerper, zgc:109842 antikoerper, igf2-A antikoerper, ins antikoerper, ins-a antikoerper, ins-b antikoerper, insulin antikoerper, insulin precursor antikoerper, insulin II antikoerper, preproinsulin antikoerper, insulin L homeolog antikoerper, insulin S homeolog antikoerper, INS antikoerper, INS-IGF2 antikoerper, ins antikoerper, Ins antikoerper, PIN antikoerper, Ins2 antikoerper, ins.L antikoerper, ins.S antikoerper
- Hintergrund
-
Target Description: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Gene Symbol: INS
- Gen-ID
- 3630
- UniProt
- P01308
- Pathways
- NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
-