PAWR Antikörper
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- Target Alle PAWR Antikörper anzeigen
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAWR Antikörper ist unkonjugiert
- Applikation
- Bitte anfragen
- Verwendungszweck
- Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,
- Top Product
- Discover our top product PAWR Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- Target
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
- Andere Bezeichnung
- Prostate Apoptosis Response protein-4 (PAWR Produkte)
- Synonyme
- MGC81382 antikoerper, pawrl antikoerper, zgc:103513 antikoerper, PAWR antikoerper, PAR4 antikoerper, Par-4 antikoerper, Par4 antikoerper, 2310001G03Rik antikoerper, pro-apoptotic WT1 regulator antikoerper, PRKC, apoptosis, WT1, regulator L homeolog antikoerper, PRKC, apoptosis, WT1, regulator antikoerper, PAWR antikoerper, pawr.L antikoerper, pawr antikoerper, Pawr antikoerper
- Hintergrund
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Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
Gene Symbol: PAWR
- Gen-ID
- 5074
- UniProt
- Q96IZ0
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