TNNI1 Antikörper

Produktnummer ABIN629823

Produktdetails anti-TNNI1 Antikörper

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: Troponin I Type 1 antibody was raised using a synthetic peptide corresponding to a region with amino acids PPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGD

Anwendungsinformationen

Applikationshinweise: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

Troponin I Type 1 Blocking Peptide, catalog no. 33R-7266, is also available for use as a blocking control in assays to test for specificity of this Troponin I Type 1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TNNI1 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu TNNI1

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Abstract: TNNI1 Produkte

Hintergrund: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.

Molekulargewicht: 21 kDa (MW of target protein)