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MCM4 Antikörper (Middle Region)

MCM4 Reaktivität: Human, Maus, Ratte, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN630173
  • Target Alle MCM4 Antikörper anzeigen
    MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
    Bindungsspezifität
    • 15
    • 11
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 92
    • 42
    • 21
    • 10
    • 10
    • 9
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    Human, Maus, Ratte, Hund
    Wirt
    • 86
    • 4
    • 3
    Kaninchen
    Klonalität
    • 91
    • 2
    Polyklonal
    Konjugat
    • 51
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCM4 Antikörper ist unkonjugiert
    Applikation
    • 71
    • 36
    • 36
    • 13
    • 13
    • 13
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    MCM4 antibody was raised against the middle region of MCM4
    Aufreinigung
    Purified
    Immunogen
    MCM4 antibody was raised using the middle region of MCM4 corresponding to a region with amino acids VYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYE
    Top Product
    Discover our top product MCM4 Primärantikörper
  • Applikationshinweise
    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    MCM4 Blocking Peptide, catalog no. 33R-9921, is also available for use as a blocking control in assays to test for specificity of this MCM4 antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM4 antibody in PBS
    Konzentration
    Lot specific
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
    Andere Bezeichnung
    MCM4 (MCM4 Produkte)
    Synonyme
    cdc21 antikoerper, CDC21 antikoerper, CDC54 antikoerper, NKCD antikoerper, NKGCD antikoerper, P1-CDC21 antikoerper, hCdc21 antikoerper, 19G antikoerper, AI325074 antikoerper, AU045576 antikoerper, Cdc21 antikoerper, Mcmd4 antikoerper, mKIAA4003 antikoerper, mcdc21 antikoerper, cb1025 antikoerper, fc12c09 antikoerper, fj85g09 antikoerper, hm:zeh1616 antikoerper, wu:fc12c09 antikoerper, wu:fj85g09 antikoerper, zeh1616 antikoerper, minichromosome maintenance complex component 4 L homeolog antikoerper, minichromosome maintenance complex component 4 S homeolog antikoerper, minichromosome maintenance complex component 4 antikoerper, mcm4.L antikoerper, mcm4.S antikoerper, MCM4 antikoerper, mcm4 antikoerper, Mcm4 antikoerper
    Hintergrund
    The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. The MCM4 gene is mapped to a region on the chromosome 8 head-to-head next to the PRkDaC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks.
    Molekulargewicht
    95 kDa (MW of target protein)
    Pathways
    DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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