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GALE Antikörper (N-Term)

GALE Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN631451
  • Target Alle GALE Antikörper anzeigen
    GALE (UDP-Galactose-4-Epimerase (GALE))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 35
    • 20
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 4
    Kaninchen
    Klonalität
    • 48
    • 2
    Polyklonal
    Konjugat
    • 21
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GALE Antikörper ist unkonjugiert
    Applikation
    • 39
    • 15
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    GALE antibody was raised against the N terminal of GALE
    Aufreinigung
    Affinity purified
    Immunogen
    GALE antibody was raised using the N terminal of GALE corresponding to a region with amino acids AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRR
    Top Product
    Discover our top product GALE Primärantikörper
  • Applikationshinweise
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    GALE Blocking Peptide, catalog no. 33R-1135, is also available for use as a blocking control in assays to test for specificity of this GALE antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GALE antibody in PBS
    Konzentration
    Lot specific
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    GALE (UDP-Galactose-4-Epimerase (GALE))
    Andere Bezeichnung
    GALE (GALE Produkte)
    Hintergrund
    GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation.
    Molekulargewicht
    38 kDa (MW of target protein)
    Pathways
    Response to Water Deprivation, Cellular Glucan Metabolic Process
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