Prohibitin Antikörper (C-Term)
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- Target Alle Prohibitin (PHB) Antikörper anzeigen
- Prohibitin (PHB)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Prohibitin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- Prohibitin antibody was raised against the C terminal of PHB
- Aufreinigung
- Affinity purified
- Immunogen
- Prohibitin antibody was raised using the C terminal of PHB corresponding to a region with amino acids AEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLS
- Top Product
- Discover our top product PHB Primärantikörper
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- Applikationshinweise
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WB: 1-2 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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Prohibitin Blocking Peptide, catalog no. 33R-1146, is also available for use as a blocking control in assays to test for specificity of this Prohibitin antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHB antibody in PBS
- Konzentration
- Lot specific
- Buffer
- PBS
- Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- Prohibitin (PHB)
- Andere Bezeichnung
- Prohibitin (PHB Produkte)
- Synonyme
- phb1 antikoerper, MGC75944 antikoerper, PHB antikoerper, Phb antikoerper, ACYPI000080 antikoerper, phb antikoerper, PHB1 antikoerper, Bap32 antikoerper, sr:nyz128 antikoerper, wu:fa18f07 antikoerper, wu:fb09f05 antikoerper, prohibitin1 antikoerper, xphb1 antikoerper, prohibitin antikoerper, prohibitin-2 antikoerper, prohibitin L homeolog antikoerper, PHB antikoerper, phb antikoerper, LOC484431 antikoerper, LOC5576054 antikoerper, Phb antikoerper, phb.L antikoerper
- Hintergrund
- Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
- Molekulargewicht
- 30 kDa (MW of target protein)
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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