FLASH Antikörper (N-Term)
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- Target Alle FLASH (CASP8AP2) Antikörper anzeigen
- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Säugetier
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FLASH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity chromatography purified
- Immunogen
- FLASH antibody was raised in rabbit using N terminus of the FLASH protein as the immunogen.
- Isotyp
- IgG
- Top Product
- Discover our top product CASP8AP2 Primärantikörper
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- Applikationshinweise
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WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- Lot specific
- Buffer
- Affinity purified IgG supplied in PBS with 0.02 % NaN3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
- Andere Bezeichnung
- FLASH (CASP8AP2 Produkte)
- Synonyme
- CASP8AP2 antikoerper, FLASH antikoerper, fc74h10 antikoerper, wu:fc74h10 antikoerper, zgc:113449 antikoerper, CED-4 antikoerper, RIP25 antikoerper, AA387232 antikoerper, D4Ertd659e antikoerper, mKIAA1315 antikoerper, caspase 8 associated protein 2 antikoerper, CASP8AP2 antikoerper, casp8ap2 antikoerper, Casp8ap2 antikoerper
- Hintergrund
- FLASH, contains a motif with oligomerizing activity whose sequence is similar to that of the Caenorhabditis elegans protein CED-4, and another domain (DRD domain) that interacts with a death-effector domain in caspase-8 or in the adapter protein. FLASH is likely a component of the DISC signalling complex and is necessary for the activation of caspase-8 in Fas-mediated apoptosis.
- Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
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