FLASH Antikörper (N-Term)
Kurzübersicht für FLASH Antikörper (N-Term) (ABIN636211)
Target
Alle FLASH (CASP8AP2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Aufreinigung
- Affinity chromatography purified
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Immunogen
- FLASH antibody was raised in rabbit using N terminus of the FLASH protein as the immunogen.
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Isotyp
- IgG
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Applikationshinweise
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WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- Lot specific
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Buffer
- Affinity purified IgG supplied in PBS with 0.02 % NaN3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
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Andere Bezeichnung
- FLASH
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Hintergrund
- FLASH, contains a motif with oligomerizing activity whose sequence is similar to that of the Caenorhabditis elegans protein CED-4, and another domain (DRD domain) that interacts with a death-effector domain in caspase-8 or in the adapter protein. FLASH is likely a component of the DISC signalling complex and is necessary for the activation of caspase-8 in Fas-mediated apoptosis.
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Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
Target
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