USP29 Antikörper (AA 660-690)

Produktnummer ABIN650701

Produktdetails anti-USP29 Antikörper

Target: USP29 (Ubiquitin Specific Peptidase 29 (USP29))

Bindungsspezifität: AA 660-690

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP29 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This USP29 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 660-690 amino acids from the Central region of human USP29.

Klon: RB4373

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu USP29

Target: USP29 (Ubiquitin Specific Peptidase 29 (USP29))

Andere Bezeichnung: USP29 (USP29 Produkte)

Synonyme: USP29 antikoerper, HOM-TES-84/86 antikoerper, Ocat antikoerper, universal stress protein antikoerper, ubiquitin specific peptidase 29 antikoerper, ubiquitin carboxyl-terminal hydrolase 29-like antikoerper, RR_RS07250 antikoerper, Usp29 antikoerper, USP29 antikoerper, LOC100341314 antikoerper, LOC100341826 antikoerper, LOC100342339 antikoerper, LOC100348359 antikoerper

Hintergrund: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Molekulargewicht: 104156

Gen-ID: 57663

NCBI Accession: NP_065954

UniProt: Q9HBJ7