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MCAM Antikörper (C-Term)

Name: MCAM Antikörper (C-Term)
SKU: ABIN650721
Price: 445.5 EUR
Availability: InStock

MCAM Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB20607 unconjugated

Western blot analysis of MC Antibody (C-term) (ABIN650721 and ABIN2839393) in cell line lysates (35 μg/lane). (MCAM Antikörper (C-Term))

MC Antibody (C-term) (ABIN650721 and ABIN2839393) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (MCAM Antikörper (C-Term))

IHC (p)

2 Abbildungen

Produktnummer ABIN650721

Datenblatt (PDF)

Target Alle MCAM Antikörper anzeigen

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Bindungsspezifität
16

12

10

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 532-558, C-Term
Reaktivität
133

53

47

14

14

9

8

7

6

2
Human
Wirt
94

63

8

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
87

80
Polyklonal
Konjugat
70

14

14

11

6

5

4

4

4

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MCAM Antikörper ist unkonjugiert
Applikation
85

80

69

43

22

20

13

10

10

5

4

4

3

3

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-558 amino acids from the C-terminal region of human MCAM.

Klon

RB20607

Isotyp

Ig Fraction

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Applikationshinweise

WB: 1:1000. IHC-P: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Andere Bezeichnung

MCAM (MCAM Produkte)

Synonyme

CD146 antikoerper, MUC18 antikoerper, Muc18 antikoerper, 1-gicerin antikoerper, AV025631 antikoerper, CD149 antikoerper, s-endo antikoerper, s-gicerin antikoerper, cd146 antikoerper, gicerin antikoerper, id:ibd3512 antikoerper, mcam antikoerper, MCAM antikoerper, melanoma cell adhesion molecule antikoerper, melanoma cell adhesion molecule b antikoerper, MCAM antikoerper, Mcam antikoerper, mcamb antikoerper

Hintergrund

MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Molekulargewicht

71607

Gen-ID

4162

NCBI Accession

NP_006491

UniProt

P43121