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MCAM Antikörper (AA 161-189)

MCAM Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB20606 unconjugated
Produktnummer ABIN650722
  • Target Alle MCAM Antikörper anzeigen
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    Bindungsspezifität
    • 16
    • 13
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 161-189
    Reaktivität
    • 133
    • 53
    • 47
    • 14
    • 14
    • 9
    • 8
    • 7
    • 6
    • 2
    Human
    Wirt
    • 94
    • 63
    • 8
    • 1
    • 1
    Kaninchen
    Klonalität
    • 87
    • 80
    Polyklonal
    Konjugat
    • 70
    • 14
    • 14
    • 11
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCAM Antikörper ist unkonjugiert
    Applikation
    • 85
    • 79
    • 69
    • 43
    • 22
    • 20
    • 13
    • 10
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human MCAM.
    Klon
    RB20606
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MCAM Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    Andere Bezeichnung
    MCAM (MCAM Produkte)
    Synonyme
    CD146 antikoerper, MUC18 antikoerper, Muc18 antikoerper, 1-gicerin antikoerper, AV025631 antikoerper, CD149 antikoerper, s-endo antikoerper, s-gicerin antikoerper, cd146 antikoerper, gicerin antikoerper, id:ibd3512 antikoerper, mcam antikoerper, MCAM antikoerper, melanoma cell adhesion molecule antikoerper, melanoma cell adhesion molecule b antikoerper, MCAM antikoerper, Mcam antikoerper, mcamb antikoerper
    Hintergrund
    MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
    Molekulargewicht
    71607
    Gen-ID
    4162
    NCBI Accession
    NP_006491
    UniProt
    P43121
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