GADD45A Antikörper (C-Term)

Produktnummer ABIN650724

Produktdetails anti-GADD45A Antikörper

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Bindungsspezifität: AA 133-165, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GADD45A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: B, Ha, M, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GADD45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the C-terminal region of human GADD45A.

Klon: RB16521

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-GADD45A Antikörper (ABIN650724)

Wu, Boonmars, Nagano, Boonjaraspinyo, Srinontong, Ratasuwan, Narong, Nielsen, Maekawa: "Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).

Details zu GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Andere Bezeichnung: GADD45A (GADD45A Produkte)

Synonyme: MGC53491 antikoerper, zgc:91795 antikoerper, gadd45a antikoerper, GADD45A antikoerper, ddit1 antikoerper, gadd45 antikoerper, GADD45 antikoerper, AA545191 antikoerper, Ddit1 antikoerper, DDIT1 antikoerper, Gadd45 antikoerper, growth arrest and DNA damage inducible alpha L homeolog antikoerper, growth arrest and DNA-damage-inducible, alpha, b antikoerper, growth arrest and DNA damage inducible alpha antikoerper, growth arrest and DNA damage-inducible protein 45 antikoerper, growth arrest and DNA-damage-inducible 45 alpha antikoerper, growth arrest and DNA-damage-inducible, alpha antikoerper, gadd45a.L antikoerper, gadd45ab antikoerper, GADD45A antikoerper, gadd45a antikoerper, GADD45 antikoerper, Gadd45a antikoerper

Hintergrund: GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45A gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.

Molekulargewicht: 18336

Gen-ID: 1647

NCBI Accession: NP_001186670, NP_001186671, NP_001915

UniProt: P24522

Pathways: p53 Signalweg, Zellzyklus