SRSF2 Antikörper (AA 76-105)

Produktnummer ABIN650729

Produktdetails anti-SRSF2 Antikörper

Target: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Bindungsspezifität: AA 76-105

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRSF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, C, M, Pig, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SFRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human SFRS2.

Klon: RB17330

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu SRSF2

Target: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Andere Bezeichnung: SFRS2 (SRSF2 Produkte)

Synonyme: PR264 antikoerper, SC-35 antikoerper, SC35 antikoerper, SFRS2 antikoerper, SFRS2A antikoerper, SRp30b antikoerper, D11Wsu175e antikoerper, MRF-1 antikoerper, Pr264 antikoerper, Sfrs10 antikoerper, Sfrs2 antikoerper, pr264 antikoerper, sc-35 antikoerper, sc35 antikoerper, sfrs2 antikoerper, sfrs2a antikoerper, srp30b antikoerper, serine and arginine rich splicing factor 2 antikoerper, serine/arginine-rich splicing factor 2 antikoerper, serine/arginine-rich splicing factor 2 L homeolog antikoerper, SRSF2 antikoerper, Srsf2 antikoerper, srsf2.L antikoerper

Hintergrund: SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway.

Molekulargewicht: 25476

Gen-ID: 6427

NCBI Accession: NP_001182356, NP_003007

UniProt: Q01130