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JNK Antikörper (pThr183, pTyr185)
MAPK8
Reaktivität: Human
DB
Wirt: Kaninchen
Polyclonal
RB28967
unconjugated
Produktnummer ABIN2839831
Produktdetails anti-JNK Antikörper
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Target
Alle JNK (MAPK8) Antikörper anzeigen
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Bindungsspezifität
Alle Epitope für JNK Antikörper
pThr183, pTyr185
Reaktivität
Alle Reaktivitäten für JNK Antikörper
Human
Wirt
Alle Wirte für JNK Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für JNK Antikörper
Polyklonal
Konjugat
Alle Konjugate für JNK Antikörper
Dieser JNK Antikörper ist unkonjugiert
Applikation
Alle Applikationen für JNK Antikörper
Dot Blot (DB)
Homologie
M, Rat, X
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This JNK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T183/Y185 of human JNK1.
Klon
RB28967
Isotyp
Ig Fraction
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Discover our top product MAPK8 Primärantikörper
Alternativen
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anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibody
MAPK8
Reaktivität: Human, Maus, Ratte, Hund, Kaninchen
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibody
MAPK8
Reaktivität: Human, Maus, Ratte, Huhn, Hund
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 151-250) antibody
MAPK8
Reaktivität: Human, Maus, Ratte, Huhn, Schwein
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
DB: 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu JNK
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Target
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Andere Bezeichnung
MAPK8 (MAPK8 Produkte )
Synonyme
JNK antikoerper, JNK-46 antikoerper, JNK1 antikoerper, JNK1A2 antikoerper, JNK21B1/2 antikoerper, PRKM8 antikoerper, SAPK1 antikoerper, SAPK1c antikoerper, AI849689 antikoerper, Prkm8 antikoerper, BSK antikoerper, BSK/DJNK antikoerper, Bsk antikoerper, CG5680 antikoerper, D-JNK antikoerper, D-junk antikoerper, DBSK/JNK antikoerper, DJNK antikoerper, DJNK/bsk antikoerper, Dmel\\CG5680 antikoerper, JNK/SAPK antikoerper, Jnk antikoerper, Junk antikoerper, SAPKa antikoerper, c-Jun antikoerper, dJNK antikoerper, jnk antikoerper, T10F20.15 antikoerper, jnk1 antikoerper, sapk1 antikoerper, mapk8 antikoerper, zgc:112379 antikoerper, JNKb antikoerper, mapk8b antikoerper, mitogen-activated protein kinase 8 antikoerper, Stress-activated protein kinase jnk-1 antikoerper, basket antikoerper, Protein kinase superfamily protein antikoerper, mitogen-activated protein kinase 8 L homeolog antikoerper, mitogen-activated protein kinase 8b antikoerper, mitogen-activated protein kinase 8B-like antikoerper, MAPK8 antikoerper, jnk-1 antikoerper, Mapk8 antikoerper, bsk antikoerper, ATMPK8 antikoerper, mapk8.L antikoerper, mapk8b antikoerper, LOC109094263 antikoerper
Hintergrund
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Molekulargewicht
48296
Gen-ID
5599
NCBI Accession
NP_001265476 , NP_002741 , NP_620634 , NP_620637
UniProt
P45983
Pathways
MAPK Signalweg , WNT Signalweg , TLR Signalweg , Fc-epsilon Rezeptor Signalübertragung , Neurotrophin Signalübertragung , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , Signaling of Hepatocyte Growth Factor Receptor , S100 Proteine
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