This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PIGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human PIGM.
PEANUT 1 antikoerper, GPI-MT-I antikoerper, 4933437L05Rik antikoerper, AI644422 antikoerper, AV302080 antikoerper, C920011G20Rik antikoerper, PIG-M antikoerper, mannosyltransferase family protein antikoerper, phosphatidylinositol glycan anchor biosynthesis class M antikoerper, phosphatidylinositol glycan anchor biosynthesis, class M antikoerper, PNT1 antikoerper, PIGM antikoerper, Pigm antikoerper
Hintergrund
PIGM encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. PIGM encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum.