FOLR2 Antikörper (AA 18-46)

Produktnummer ABIN651222

Produktdetails anti-FOLR2 Antikörper

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Bindungsspezifität: AA 18-46

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids of human FOLR2.

Klon: RB24013

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Referenzen für anti-FOLR2 Antikörper (ABIN651222)

Puligujja, McMillan, Kendrick, Li, Balkundi, Smith, Veerubhotla, Edagwa, Kabanov, Bronich, Gendelman, Liu: "Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 9, Issue 8, pp. 1263-73, (2013) (PubMed).

Details zu FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Andere Bezeichnung: FOLR2 (FOLR2 Produkte)

Synonyme: FOLR2 antikoerper, BETA-HFR antikoerper, FBP antikoerper, FBP/PL-1 antikoerper, FR-BETA antikoerper, FR-P3 antikoerper, FBP2 antikoerper, Folbp-2 antikoerper, Folbp2 antikoerper, folate receptor 1 antikoerper, folate receptor beta antikoerper, folate receptor 2 (fetal) antikoerper, FOLR1 antikoerper, FOLR2 antikoerper, Folr2 antikoerper

Hintergrund: FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

Molekulargewicht: 29280

Gen-ID: 2350

NCBI Accession: NP_000794, NP_001107006, NP_001107007, NP_001107008

UniProt: P14207

Pathways: Dicarboxylic Acid Transport