Geminin Antikörper (AA 96-123)

Produktnummer ABIN651420

Produktdetails anti-Geminin Antikörper

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Bindungsspezifität: AA 96-123

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Geminin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GMNN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the Central region of human GMNN.

Klon: RB20074

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Geminin

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Andere Bezeichnung: GMNN (GMNN Produkte)

Synonyme: CG3183 antikoerper, Dm Geminin antikoerper, Dm geminin antikoerper, Dmel\\CG3183 antikoerper, Gem antikoerper, Geminin antikoerper, anon-WO0257455.1 antikoerper, gem antikoerper, l(2)k14019 antikoerper, v(2)k09107 antikoerper, sb:cb254 antikoerper, zgc:66217 antikoerper, GB16871 antikoerper, GMNN antikoerper, geminin antikoerper, dyak_GLEANR_833 antikoerper, DyakGE24654 antikoerper, GE24654 antikoerper, LOC100049517 antikoerper, AW546347 antikoerper, geminin, DNA replication inhibitor antikoerper, CG3183 gene product from transcript CG3183-RA antikoerper, geminin antikoerper, GE24654 gene product from transcript GE24654-RA antikoerper, GMNN antikoerper, geminin antikoerper, gmnn antikoerper, LOC410093 antikoerper, Dyak\geminin antikoerper, Gmnn antikoerper

Hintergrund: GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

Molekulargewicht: 23565

Gen-ID: 51053

NCBI Accession: NP_001238918, NP_001238919, NP_001238920, NP_056979

UniProt: O75496

Pathways: EGFR Signaling Pathway, DNA Replication