Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

AXIN2 Antikörper (C-Term)

AXIN2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB26798 unconjugated
Produktnummer ABIN651608
  • Target Alle AXIN2 Antikörper anzeigen
    AXIN2 (Axin 2 (AXIN2))
    Bindungsspezifität
    • 15
    • 13
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 816-843, C-Term
    Reaktivität
    • 70
    • 53
    • 40
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 83
    • 2
    Kaninchen
    Klonalität
    • 74
    • 11
    Polyklonal
    Konjugat
    • 24
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AXIN2 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 38
    • 30
    • 13
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This AXIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human AXIN2.
    Klon
    RB26798
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product AXIN2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    AXIN2 (Axin 2 (AXIN2))
    Andere Bezeichnung
    AXIN2 (AXIN2 Produkte)
    Synonyme
    AXIL antikoerper, ODCRCS antikoerper, axil antikoerper, wu:fb37c08 antikoerper, zgc:111942 antikoerper, axin-2 antikoerper, xarp antikoerper, MGC81576 antikoerper, arp-A antikoerper, axin2 antikoerper, Axi1 antikoerper, Axil antikoerper, Conductin antikoerper, axin 2 antikoerper, axin 2 (conductin, axil) antikoerper, axin 2 (conductin, axil) S homeolog antikoerper, AXIN2 antikoerper, axin2 antikoerper, axin2.S antikoerper, Axin2 antikoerper
    Hintergrund
    The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
    Molekulargewicht
    93558
    Gen-ID
    8313
    NCBI Accession
    NP_004646
    UniProt
    Q9Y2T1
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
Sie sind hier:
Kundenservice