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IPO7 Antikörper (N-Term)

IPO7 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB26876 unconjugated
Produktnummer ABIN651626
  • Target Alle IPO7 Antikörper anzeigen
    IPO7 (Importin 7 (IPO7))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 142-169, N-Term
    Reaktivität
    • 49
    • 20
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 47
    • 1
    • 1
    Kaninchen
    Klonalität
    • 48
    • 1
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IPO7 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 19
    • 19
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This IPO7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the N-terminal region of human IPO7.
    Klon
    RB26876
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    IPO7 (Importin 7 (IPO7))
    Andere Bezeichnung
    IPO7 (IPO7 Produkte)
    Synonyme
    fb33d09 antikoerper, wu:fb33d09 antikoerper, zgc:66425 antikoerper, zgc:76878 antikoerper, imp7 antikoerper, ranbp7 antikoerper, Imp7 antikoerper, RANBP7 antikoerper, A330055O14Rik antikoerper, C330016G14 antikoerper, Ranbp7 antikoerper, importin 7 antikoerper, importin 7 S homeolog antikoerper, importin-7 antikoerper, karyopherin antikoerper, ipo7 antikoerper, ipo7.S antikoerper, IPO7 antikoerper, CpipJ_CPIJ002096 antikoerper, PTRG_08544 antikoerper, SJAG_03693 antikoerper, NAEGRDRAFT_71372 antikoerper, VDBG_01971 antikoerper, MGYG_08162 antikoerper, Tsp_01943 antikoerper, Tsp_01946 antikoerper, Ipo7 antikoerper
    Hintergrund
    The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
    Molekulargewicht
    119517
    Gen-ID
    10527
    NCBI Accession
    NP_006382
    UniProt
    O95373
    Pathways
    Protein targeting to Nucleus
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