TNIP3 Antikörper (N-Term)

Produktnummer ABIN651787

Produktdetails anti-TNIP3 Antikörper

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Bindungsspezifität: AA 74-102, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human TNIP3.

Klon: RB27057

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu TNIP3

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Andere Bezeichnung: TNIP3 (TNIP3 Produkte)

Synonyme: ABIN-3 antikoerper, LIND antikoerper, 9030611K07Rik antikoerper, TNIP3 antikoerper, TNFAIP3 interacting protein 3 antikoerper, TNIP3 antikoerper, Tnip3 antikoerper

Hintergrund: TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. It Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Molekulargewicht: 38943

Gen-ID: 79931

NCBI Accession: NP_001122315, NP_001231693, NP_079149

UniProt: Q96KP6

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin