SLAMF7 Antikörper (AA 58-85)

Produktnummer ABIN651870

Produktdetails anti-SLAMF7 Antikörper

Target: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Bindungsspezifität: AA 58-85

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLAMF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLAMF7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-85 amino acids from the Central region of human SLAMF7.

Klon: RB22341

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu SLAMF7

Target: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Andere Bezeichnung: SLAMF7 (SLAMF7 Produkte)

Synonyme: RGD1560190 antikoerper, SLAMF7 antikoerper, slaf7 antikoerper, 19A antikoerper, CD319 antikoerper, CRACC antikoerper, CS1 antikoerper, 19A24 antikoerper, 4930560D03Rik antikoerper, SLAM family member 7 antikoerper, Slamf7 antikoerper, SLAMF7 antikoerper, slaf7 antikoerper

Hintergrund: SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.

Molekulargewicht: 37421

Gen-ID: 57823

NCBI Accession: NP_067004

UniProt: Q9NQ25