FOXP2 Antikörper (AA 657-684)

Produktnummer ABIN651939

Produktdetails anti-FOXP2 Antikörper

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Bindungsspezifität: AA 657-684

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FOXP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-684 amino acids of human FOXP2.

Klon: RB21207

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-FOXP2 Antikörper (ABIN651939)

Vibulyaseck, Fujita, Luo, Tran, Oh-Nishi, Ono, Hirano, Sugihara: "Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum." in: The Journal of comparative neurology, Vol. 525, Issue 14, pp. 2971-2990, (2018) (PubMed).

Fujita, Morita, Furuichi, Sugihara: "Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 45, pp. 15688-703, (2012) (PubMed).

Details zu FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Andere Bezeichnung: FOXP2 (FOXP2 Produkte)

Synonyme: CAGH44 antikoerper, SPCH1 antikoerper, TNRC10 antikoerper, 2810043D05Rik antikoerper, AI449000 antikoerper, CAG-16 antikoerper, D0Kist7 antikoerper, RGD1559697 antikoerper, FOXP2 antikoerper, spch1 antikoerper, cagh44 antikoerper, tnrc10 antikoerper, xlFoxP2 antikoerper, foxP2 antikoerper, foxP antikoerper, Foxp2 antikoerper, foxP2b antikoerper, foxp2a antikoerper, forkhead box P2 antikoerper, lmw-gs antikoerper, forkhead box transcription factor antikoerper, forkhead box P2 L homeolog antikoerper, FOXP2 antikoerper, Foxp2 antikoerper, foxp2 antikoerper, foxP2 antikoerper, foxp1c antikoerper, foxp2.L antikoerper

Hintergrund: FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Molekulargewicht: 79919

Gen-ID: 93986

NCBI Accession: NP_001166237, NP_001166238, NP_055306, NP_683696, NP_683697, NP_683698

UniProt: O15409