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SIRT3 Antikörper (C-Term)

Name: SIRT3 Antikörper (C-Term)
SKU: ABIN652184
Price: 445.5 EUR
Availability: InStock

SIRT3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB25945 unconjugated

Anti-Mouse Sirt3 Antibody (C-term) at 1:2000 dilution + mouse liver lysate Lysates/proteins at 20 μg per lane. (SIRT3 Antikörper (C-Term))

Sirt3 Antibody (C-term) (ABIN652184 and ABIN2840670) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (SIRT3 Antikörper (C-Term))

IHC (p)

Anti-Sirt3 Antibody (C-term) at 1:64000 dilution + mouse liver lysate Lysates/proteins at 20 μg per lane. (SIRT3 Antikörper (C-Term))

Anti-Sirt3 Antibody (C-term) at 1:2000 dilution + mouse liver lysate Lysates/proteins at 20 μg per lane. (SIRT3 Antikörper (C-Term))

Anti-Sirt3 Antibody (C-term) at 1:2000 dilution + CHO whole cell lysate Lysates/proteins at 20 μg per lane. (SIRT3 Antikörper (C-Term))

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN652184

Datenblatt (PDF)

Target Alle SIRT3 Antikörper anzeigen

SIRT3 (Sirtuin 3 (SIRT3))
Bindungsspezifität
16

9

8

7

7

7

6

6

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 304-334, C-Term
Reaktivität
93

40

18

9

5

4

4

4

3

3

2

2

2
Human, Maus
Wirt
82

16

2

2

2
Kaninchen
Passende Sekundärantikörper
Klonalität
90

15
Polyklonal
Konjugat
56

15

12

6

5

5

1

1

1

1

1

1
Dieser SIRT3 Antikörper ist unkonjugiert
Applikation
91

62

42

10

8

7

6

5

5

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This Sirt3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-334 amino acids from the C-terminal region of Mouse Sirt3.

Klon

RB25945

Isotyp

Ig Fraction

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anti-Sirtuin 3 (SIRT3) (AA 250-279) antibody
SIRT3 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 304-334) antibody
SIRT3 Reaktivität: Human, Maus, Hamster WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 5-257) antibody
SIRT3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sirtuin 3 (SIRT3) (AA 20-130) antibody
SIRT3 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:2000. WB: 1:64000. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid freeze-thaw cycles.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit

6 months
Chen, Liu, Li, Wang, Liu, Li, Zhang, Bu: "Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD." in: PLoS ONE, Vol. 10, Issue 3, pp. e0118909, (2015) (PubMed).

Kawamura, Uchijima, Horike, Tonami, Nishiyama, Amano, Asano, Kurihara, Kurihara: "Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest." in: The Journal of clinical investigation, Vol. 120, Issue 8, pp. 2817-28, (2010) (PubMed).
Target

SIRT3 (Sirtuin 3 (SIRT3))

Andere Bezeichnung

Sirt3 (SIRT3 Produkte)

Synonyme

zgc:158774 antikoerper, sirtuin antikoerper, SIR2L3 antikoerper, 2310003L23Rik antikoerper, AI848213 antikoerper, Sir2l3 antikoerper, sirtuin 3 antikoerper, sirt3 antikoerper, SIRT3 antikoerper, Sirt3 antikoerper

Hintergrund

SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.

Molekulargewicht

36615

Gen-ID

64384

NCBI Accession

NP_001120823, NP_001171275, NP_071878

UniProt

Q8R104