GLS2 Antikörper (AA 498-524)

Produktnummer ABIN652216

Produktdetails anti-GLS2 Antikörper

Target: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Bindungsspezifität: AA 498-524

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GLS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-524 amino acids of human GLS2.

Klon: RB20072

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P-Leica: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-GLS2 Antikörper (ABIN652216)

Shroff, Eberlin, Dang, Gouw, Gabay, Adam, Bellovin, Tran, Philbrick, Garcia-Ocana, Casey, Li, Dang, Zare, Felsher: "MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 21, pp. 6539-44, (2015) (PubMed).

Details zu GLS2

Target: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Andere Bezeichnung: GLS2 (GLS2 Produkte)

Synonyme: si:ch211-216k22.10 antikoerper, GA antikoerper, GLS antikoerper, LGA antikoerper, hLGA antikoerper, A330074B06Rik antikoerper, AI195532 antikoerper, Lga antikoerper, Ga antikoerper, glutaminase 2 antikoerper, glutaminase 2a (liver, mitochondrial) antikoerper, glutaminase 2 (liver, mitochondrial) antikoerper, glsA2 antikoerper, LOAG_03311 antikoerper, gls2a antikoerper, GLS2 antikoerper, Gls2 antikoerper

Hintergrund: The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene. [provided by RefSeq].

Molekulargewicht: 66323

Gen-ID: 27165

NCBI Accession: NP_001267727, NP_037399

UniProt: Q9UI32

Pathways: Dicarboxylic Acid Transport, Warburg Effekt