TTR Antikörper (C-Term)

Produktnummer ABIN652227

Produktdetails anti-TTR Antikörper

Target: TTR (Transthyretin (TTR))

Bindungsspezifität: AA 71-98, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TTR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the C-terminal region of human TTR.

Klon: RB19657

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:2000. IHC-P: 1:25. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: TTR (TTR Produkte)

Synonyme: zgc:103583 antikoerper, TTR antikoerper, LOC100226992 antikoerper, CTS antikoerper, CTS1 antikoerper, HsT2651 antikoerper, PALB antikoerper, TBPA antikoerper, AA408768 antikoerper, AI787086 antikoerper, D17860 antikoerper, prealbumin antikoerper, Lr1 antikoerper, Tbpa antikoerper, Prealbumin antikoerper, xTTR antikoerper, transthyretin (prealbumin, amyloidosis type I) antikoerper, transthyretin antikoerper, Transthyretin antikoerper, transthyretin (prealbumin, amyloidosis type 1) antikoerper, transthyretin-like antikoerper, transthyretin L homeolog antikoerper, ttr antikoerper, TTR antikoerper, vpb38 antikoerper, MRAD2831_RS38185 antikoerper, Caci_4246 antikoerper, LOC100226992 antikoerper, Ttr antikoerper, ttr.L antikoerper

Hintergrund: Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Molekulargewicht: 15887

Gen-ID: 7276

NCBI Accession: NP_000362

UniProt: P02766

Pathways: Hormone Transport