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MLF1 Antikörper (C-Term)

MLF1 Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18643 unconjugated
Produktnummer ABIN652233
  • Target Alle MLF1 Antikörper anzeigen
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    Bindungsspezifität
    • 13
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 215-244, C-Term
    Reaktivität
    • 68
    • 45
    • 20
    • 1
    • 1
    Human, Maus
    Wirt
    • 65
    • 5
    Kaninchen
    Klonalität
    • 67
    • 3
    Polyklonal
    Konjugat
    • 39
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MLF1 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 24
    • 21
    • 15
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human MLF1.
    Klon
    RB18643
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MLF1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    Andere Bezeichnung
    MLF1 (MLF1 Produkte)
    Hintergrund
    MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
    Molekulargewicht
    30627
    Gen-ID
    4291
    NCBI Accession
    NP_001123628, NP_001123629, NP_001182361, NP_001182362, NP_001182363, NP_071888
    UniProt
    P58340
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