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SPHK1 Antikörper (C-Term)

Name: SPHK1 Antikörper (C-Term)
SKU: ABIN652302
Price: 445.5 EUR
Availability: InStock

SPHK1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB15395 unconjugated

Western blot analysis of SPHK1 Antibody (C-term ) (ABIN652302 and ABIN2837969) in 293 cell line lysates (35 μg/lane). (SPHK1 Antikörper (C-Term))

SPHK1 Antibody (C-term ) (ABIN652302 and ABIN2837969) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram). (SPHK1 Antikörper (C-Term))

FACS

Western blot analysis of SPHK1 (arrow) using rabbit polyclonal SPHK1 Antibody (C-term ) (ABIN652302 and ABIN2837969). (SPHK1 Antikörper (C-Term))

SPHK1 Antibody (C-term ) (ABIN652302 and ABIN2837969) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. (SPHK1 Antikörper (C-Term))

IHC (p)

4 Abbildungen

Produktnummer ABIN652302

Datenblatt (PDF)

Target Alle SPHK1 Antikörper anzeigen

SPHK1 (Sphingosine Kinase 1 (SPHK1))
Bindungsspezifität
15

9

8

7

7

7

7

6

6

6

5

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 313-343, C-Term
Reaktivität
101

48

43

9

3

2

2

2

1

1

1

1
Human
Wirt
92

9

1
Kaninchen
Passende Sekundärantikörper
Klonalität
88

14
Polyklonal
Konjugat
51

7

5

4

3

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1
Dieser SPHK1 Antikörper ist unkonjugiert
Applikation
69

41

24

18

13

13

11

10

4

3

3

2

2

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This SPHK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-343 amino acids from the C-terminal region of human SPHK1.

Klon

RB15395

Isotyp

Ig Fraction

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SPHK1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB03621 unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibody
SPHK1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1D6 unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30), (N-Term) antibody
SPHK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB3619 unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343) antibody
SPHK1 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibody
SPHK1 Reaktivität: Human, Maus, Ratte, Primate WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 148-398) antibody
SPHK1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibody
SPHK1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 59-89), (N-Term) antibody
SPHK1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15394 unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 50-384) antibody
SPHK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30) antibody
SPHK1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

SPHK1 (Sphingosine Kinase 1 (SPHK1))

Andere Bezeichnung

SPHK1 (SPHK1 Produkte)

Synonyme

CG1747 antikoerper, Dmel\\CG1747 antikoerper, SK1 antikoerper, Sphk1 antikoerper, SPHK1 antikoerper, F18E5.160 antikoerper, F18E5_160 antikoerper, sphingosine kinase 1 antikoerper, SPHK antikoerper, 1110006G24Rik antikoerper, Sk1 antikoerper, Spk1 antikoerper, Sphingosine kinase 1 antikoerper, sphingosine kinase 1 antikoerper, sphingosine kinase 1 L homeolog antikoerper, Sk1 antikoerper, SPHK1 antikoerper, sphk1.L antikoerper, Sphk1 antikoerper

Hintergrund

SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.

Gen-ID

8877

NCBI Accession

NP_001136073, NP_001136074, NP_068807, NP_892010

UniProt

Q9NYA1

Pathways

VEGF Signaling