MUC20 Antikörper (C-Term)

Produktnummer ABIN652400

Produktdetails anti-MUC20 Antikörper

Target: MUC20 (Mucin 20, Cell Surface Associated (MUC20))

Bindungsspezifität: AA 654-684, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human MUC20.

Klon: RB13033

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P-Leica: 1:500. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MUC20 Antikörper (ABIN652400)

Uchino, Woodward, Argüeso: "Differential effect of rebamipide on transmembrane mucin biosynthesis in stratified ocular surface epithelial cells." in: Experimental eye research, Vol. 153, pp. 1-7, (2017) (PubMed).

Ohmori, Fujii, Kadochi, Mori, Nishiguchi, Fujiwara, Kishi, Sasaki, Kuniyasu: "Elaidic Acid, a Trans-Fatty Acid, Enhances the Metastasis of Colorectal Cancer Cells." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 84, Issue 3, pp. 144-151, (2017) (PubMed).

Woodward, Argüeso: "Expression analysis of the transmembrane mucin MUC20 in human corneal and conjunctival epithelia." in: Investigative ophthalmology & visual science, Vol. 55, Issue 10, pp. 6132-8, (2014) (PubMed).

Details zu MUC20

Target: MUC20 (Mucin 20, Cell Surface Associated (MUC20))

Andere Bezeichnung: MUC20 (MUC20 Produkte)

Synonyme: BC026367 antikoerper, MUC-20 antikoerper, mucin-20 antikoerper, mucin 20 antikoerper, mucin 20, cell surface associated antikoerper, LOC750119 antikoerper, Muc20 antikoerper, MUC20 antikoerper

Hintergrund: This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 71982

Gen-ID: 200958

UniProt: Q8N307