This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This NEK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the Central region of human NEK3.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
McHale, Tomaszewski, Puthiyaveettil, Livolsi, Clevenger: "Altered expression of prolactin receptor-associated signaling proteins in human breast carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 5, pp. 565-71, (2008) (PubMed).
HSPK36 antikoerper, ATNEK3 antikoerper, NIMA-RELATED KINASE3 antikoerper, NIMA-related kinase 3 antikoerper, T8M17.60 antikoerper, T8M17_60 antikoerper, NIMA related kinase 3 antikoerper, NIMA (never in mitosis gene a)-related expressed kinase 3 antikoerper, NIMA-related kinase 3 S homeolog antikoerper, NIMA-related kinase 3 antikoerper, NEK3 antikoerper, Nek3 antikoerper, nek3.S antikoerper
Hintergrund
In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. NEK3 is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm.