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IFNAR1 Antikörper (AA 162-188)

Name: IFNAR1 Antikörper (AA 162-188)
SKU: ABIN652490
Price: 445.5 EUR
Availability: InStock

IFNAR1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB21945 unconjugated

All lanes : Anti-IFNAR1 Antibody (Center) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: 293 whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: H. (IFNAR1 Antikörper (AA 162-188))

Overlay histogram showing K562 cells stained with C(green line). (IFNAR1 Antikörper (AA 162-188))

FACS

All lanes : Anti-IFNAR1 Antibody (Center) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: 293T whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: human brain lysate Lane 5: human heart lysate Lane 6: K562 whole cell lysate Lysates/proteins at 20 μg per lane. (IFNAR1 Antikörper (AA 162-188))

Immunohistochemical analysis of paraffin-embedded human brain tissue using C performed on the Leica® BOND RXm. (IFNAR1 Antikörper (AA 162-188))

IHC (p)

4 Abbildungen

(1 reference)

Produktnummer ABIN652490

Datenblatt (PDF)

Target Alle IFNAR1 Antikörper anzeigen

IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
Bindungsspezifität
21

16

13

8

7

4

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 162-188
Reaktivität
90

29

24

2

2

1

1
Human
Wirt
84

21

1
Kaninchen
Passende Sekundärantikörper
Klonalität
77

28

1
Polyklonal
Konjugat
48

8

4

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1
Dieser IFNAR1 Antikörper ist unkonjugiert
Applikation
43

28

27

25

25

25

9

7

7

5

4

3

2

2

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This IFNAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-188 amino acids of human IFNAR1.

Klon

RB21945

Isotyp

IgG

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Applikationshinweise

WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Dendrou, Cortes, Shipman, Evans, Attfield, Jostins, Barber, Kaur, Kuttikkatte, Leach, Desel, Faergeman, Cheeseman, Neville, Sawcer, Compston, Johnson, Everett, Bell, Karpe, Ultsch, Eigenbrot, McVean et al.: "Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. ..." in: Science translational medicine, Vol. 8, Issue 363, pp. 363ra149, (2017) (PubMed).
Target

IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Andere Bezeichnung

IFNAR1 (IFNAR1 Produkte)

Synonyme

ifnar1 antikoerper, IFNAR1 antikoerper, CD118 antikoerper, Ifar antikoerper, Ifnar antikoerper, Ifrc antikoerper, Infar antikoerper, AVP antikoerper, IFN-alpha-REC antikoerper, IFNAR antikoerper, IFNBR antikoerper, IFRC antikoerper, IFN-R-1 antikoerper, interferon alpha and beta receptor subunit 1 antikoerper, interferon-alpha/beta receptor alpha chain-like antikoerper, interferon (alpha and beta) receptor 1 antikoerper, interferon alpha/beta receptor 1 antikoerper, IFNAR1 antikoerper, ifnar1 antikoerper, Ifnar1 antikoerper, LOC609830 antikoerper

Hintergrund

IFNAR1 is the receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha-and beta-subunits themselves.

Molekulargewicht

63525

Gen-ID

3454

NCBI Accession

NP_000620

UniProt

P17181

Pathways

JAK-STAT Signalweg, Hepatitis C