Gasdermin B Antikörper (AA 208-237)

Produktnummer ABIN652499

Produktdetails anti-Gasdermin B Antikörper

Target: Gasdermin B (GSDMB)

Bindungsspezifität: AA 208-237

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gasdermin B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSDMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human GSDMB.

Klon: RB22342

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Gasdermin B Antikörper (ABIN652499)

Das, Miller, Beppu, Mueller, McGeough, Vuong, Karta, Rosenthal, Chouiali, Doherty, Kurten, Hamid, Hoffman, Broide: "GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 46, pp. 13132-13137, (2018) (PubMed).

Details zu Gasdermin B

Target: Gasdermin B (GSDMB)

Andere Bezeichnung: GSDMB (GSDMB Produkte)

Synonyme: GSDML antikoerper, PRO2521 antikoerper, gasdermin B antikoerper, GSDMB antikoerper

Hintergrund: GSDMB is a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.

Molekulargewicht: 46786

Gen-ID: 55876

NCBI Accession: NP_001035936, NP_001159430, NP_001159431, NP_061000

UniProt: Q8TAX9