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Retinoblastoma 1 Antikörper (C-Term)

Name: Retinoblastoma 1 Antikörper (C-Term)
SKU: ABIN652516
Price: 445.5 EUR
Availability: InStock

RB1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20715 unconjugated

All lanes : Anti-RB1 Antibody (C-term) at 1:8000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. (Retinoblastoma 1 Antikörper (C-Term))

RB1 Antibody (C-term) (ABIN652516 and ABIN2842345) flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram). (Retinoblastoma 1 Antikörper (C-Term))

FACS

Western blot analysis of RB1 Antibody (C-term) (ABIN652516 and ABIN2842345) in 293 cell line lysates (35 μg/lane). (Retinoblastoma 1 Antikörper (C-Term))

Formalin-fixed and paraffin-embedded human testis tissue reacted with RB1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (Retinoblastoma 1 Antikörper (C-Term))

IHC (p)

4 Abbildungen

Produktnummer ABIN652516

Datenblatt (PDF)

Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen

Retinoblastoma 1 (RB1)
Bindungsspezifität
35

26

24

23

21

21

18

15

11

11

10

6

6

6

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 858-886, C-Term
Reaktivität
289

120

105

6

4

4

3

3

3

2

2

1

1

1
Human
Wirt
252

39
Kaninchen
Passende Sekundärantikörper
Klonalität
247

44
Polyklonal
Konjugat
133

17

16

16

11

10

6

6

6

6

6

6

6

6

6

6

6

4

4

2

2

2

2

1

1

1

1

1

1
Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
Applikation
209

119

107

80

79

37

31

28

28

21

16

8

8

6

6

6

4

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

Rat

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This RB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 858-886 amino acids from the C-terminal region of human RB1.

Klon

RB20715

Isotyp

Ig Fraction

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anti-Retinoblastoma 1 (RB1) (pSer780) antibody
RB1 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated

Applikationshinweise

WB: 1:8000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

Retinoblastoma 1 (RB1)

Andere Bezeichnung

RB1 (RB1 Produkte)

Synonyme

OSRC antikoerper, RB antikoerper, p105-Rb antikoerper, pRb antikoerper, pp110 antikoerper, Rb antikoerper, Rb-1 antikoerper, P105-RB antikoerper, PP110 antikoerper, RB11 antikoerper, zgc:154147 antikoerper, RB transcriptional corepressor 1 antikoerper, RB transcriptional corepressor like 1 antikoerper, retinoblastoma 1 antikoerper, RB1 antikoerper, RBL1 antikoerper, Rb1 antikoerper, rb1 antikoerper

Hintergrund

RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.

Molekulargewicht

106159

Gen-ID

5925

NCBI Accession

NP_000312

UniProt

P06400

Pathways

Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie