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PKC alpha Antikörper (N-Term)

Name: PKC alpha Antikörper (N-Term)
SKU: ABIN652517
Price: 445.5 EUR
Availability: InStock

PKCa Reaktivität: Human, Maus WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB20769 unconjugated

Western blot analysis of PRKCA Antibody (N-term) (ABIN652517 and ABIN2842346) in mouse NIH-3T3 cell line lysates (35 μg/lane). (PKC alpha Antikörper (N-Term))

PRKCA Antibody (N-term) (ABIN652517 and ABIN2842346) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram). (PKC alpha Antikörper (N-Term))

FACS

Confocal immunofluorescent analysis of PRKCA Antibody (N-term) (ABIN652517 and ABIN2842346) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (PKC alpha Antikörper (N-Term))

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PRKCA Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PKC alpha Antikörper (N-Term))

IHC (p)

4 Abbildungen

Produktnummer ABIN652517

Datenblatt (PDF)

Target Alle PKC alpha (PKCa) Antikörper anzeigen

PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
Bindungsspezifität
23

21

16

12

9

9

8

7

7

6

5

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 75-103, N-Term
Reaktivität
164

90

68

5

5

5

3

2

2

2

2

1

1

1

1
Human, Maus
Wirt
159

13

1
Kaninchen
Passende Sekundärantikörper
Klonalität
140

32
Polyklonal
Konjugat
82

14

10

7

7

6

6

6

6

6

4

4

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser PKC alpha Antikörper ist unkonjugiert
Applikation
114

66

54

21

19

16

15

15

14

7

5

2

2

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie

B, Rb, Rat

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This PRKCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human PRKCA.

Klon

RB20769

Isotyp

Ig Fraction

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Applikationshinweise

IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Andere Bezeichnung

PRKCA (PKCa Produkte)

Synonyme

pkc-alpha antikoerper, pkcalpha antikoerper, im:7139045 antikoerper, si:dkey-8l19.1 antikoerper, LOC100219195 antikoerper, AAG6 antikoerper, PKC-alpha antikoerper, PKCA antikoerper, PRKACA antikoerper, AI875142 antikoerper, Pkca antikoerper, PKRCA antikoerper, protein kinase C alpha antikoerper, protein kinase C, alpha L homeolog antikoerper, protein kinase C, alpha antikoerper, PRKCA antikoerper, prkca.L antikoerper, prkca antikoerper, Prkca antikoerper

Hintergrund

PRKCA is a calcium-activated, phospholipid-dependent, serine-and threonine-specific enzyme. It may play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

Molekulargewicht

76750

Gen-ID

5578

NCBI Accession

NP_002728

UniProt

P17252

Pathways

WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling